Thursday, September 14, 2023

Do Testosterone Boosters Work?

Do Over The Counter Testosterone Boosters Work?

Boosting testosterone levels using supplements often marketed as testosterone boosters remains a popular trend. These supplements, easily accessible online or over-the-counter from stores like GNC , claim to elevate testosterone levels and alleviate symptoms of low testosterone. Yet, the efficacy of these supplements remains uncertain. While some studies indicate a modest impact on testosterone levels, the results are inconclusive and short-lived, creating a debate within the scientific community about their effectiveness.

Most of these supplements contain essential vitamins and minerals like zinc, magnesium, and vitamin D, crucial for testosterone production. However, multiple studies have refuted their actual ability to elevate testosterone levels. Instead, these supplements might assist in optimizing the body's natural production but are unlikely to significantly increase testosterone levels beyond baseline. Moreover, these products are not regulated by the FDA, raising concerns about their safety and efficacy.

Recognizing the Signs of Low Testosterone

Low testosterone manifests through various symptoms such as reduced body hair, fatigue, mood swings, decreased libido, and weight gain. Understandably, individuals experiencing these signs might seek remedies, often lured by the extensive marketing of testosterone boosters.

Assessing the Effectiveness of Testosterone Boosters Numerous studies examining popular ingredients like Fenugreek or Zinc within these supplements have shown mixed results. For instance, while Fenugreek has exhibited mild increases in testosterone levels in some studies, others haven't confirmed its efficacy. Zinc, although linked to testosterone production, lacks evidence supporting its direct effect on elevating testosterone levels. Excessive intake of zinc, found in some boosters, may lead to health complications. See the following:

“anemia, neutropenia, and altered immune functions.”  Irani M, Sadeghi R, Amirian M, et al. The effect of folate and folate plus zinc supplementation on endocrine parameters and sperm characteristics in sub-fertile men: A systematic review and meta-analysis. Urol J 2017;14(5):4069–4078; doi: 10.22037/uj.v14i5.3772 CrossrefMedline

 

Scientific Findings on Testosterone Boosters

Studies published in reputable journals like The Journal of Sexual Medicine have shown inconclusive results, casting doubt on the effectiveness of these supplements. Researchers caution against relying on testosterone boosters due to the scarcity of comprehensive human studies confirming their efficacy.

For example:

 

  • Park HJ, Lee KS, Lee EK, et al. Efficacy and safety of a mixed extract of Trigonella Foenum-Graecum seed and Lespedeza Cuneata in the treatment of testosterone deficiency syndrome: A randomized, double-blind, placebo-controlled clinical trial. World J Mens Health 2018;36(3):230; doi: 10.5534/wjmh.170004 CrossrefMedline

 

Also, in a study published in the The Journal of Sexual Medicine, there was no real scientific evidence of Testosterone boosters having any significant impact on elevating T levels for men.

Volume 16, Issue 2, February 2019, Pages 203-212 the conclusion was that there was no evidence of any T booster being effective in treating sub optimal/Low Testosterone levels. The following is their conclusion:

“T-Boosters are easily available online. Our investigation revealed that limited human studies have evaluated T-Boosters, resulting in no definitive findings of efficacy. In the absence of additional human studies, patients should be cautioned before considering T-Boosters, given the availability of highly effective therapies approved by the Food and Drug Administration.”

 

Balasubramanian A, Thirumavalavan N, Srivatsav A, et al. Testosterone Imposters: An Analysis of Popular Online Testosterone Boosting Supplements. J Sex Med 2019;16:203–212.

 

 

Testosterone Boosters vs.
Testosterone Replacement Therapy (TRT)

The fundamental distinction lies in accessibility and regulation. Testosterone boosters are readily available over-the-counter, often comprising vitamins and herbal extracts. In contrast, Testosterone Replacement Therapy (TRT) involves physician-monitored prescription medication, offering a regulated and supervised approach to address low testosterone levels.

For those considering TRT as a potential treatment, consulting with a licensed physician knowledgeable in hormone replacement therapy is essential. If you wish to explore treatment options for low testosterone or learn more about TRT or HCG to increase testosterone levels or to fight side effects such as Testicular atrophy, our office offers personalized consultations to guide you through the process.

In another study titled “Testosterone Boosting’ Supplements Composition and Claims Are not Supported by the Academic Literature”

Chase G. Clemesha,1 Hatim Thaker,corresponding author2 and Mary K. Samplaski2

It was concluded  that “Ninety percent of "T booster" supplements had claimed to boost Testosterone but, only 24.8% of these had and data to support any of their those claims. And a total of 10.1% contained some components of their formula with data that showed a negative effect on Testosterone levels. Many of these so called “boosters” had supra-therapeutic doses of vitamins and minerals, so be careful of that as well. Some were even over the UL which could lead to adverse health complications. Consumers need to be well informed that their "T boosting" supplements may not actually have the ingredients to support these wild claims.”  It would seem that research has shown that most of all of these Testosterone boosters we see in stores and online, have no real impact on testosterone levels in men.

The Importance of Consulting Healthcare Providers While  TRT may be a viable treatment option for low testosterone, its administration requires expert supervision. Men taking over-the-counter testosterone boosters are exposed to potential side effects without the guidance of a healthcare professional. Seeking advice from a licensed healthcare provider before considering any supplement is crucial, especially to avoid interactions with other medications.

The Role of Lifestyle in Testosterone Maintenance

Lifestyle modifications like regular exercise, healthy eating, sufficient sleep, and avoiding harmful substances like alcohol and tobacco can positively influence natural testosterone production.

Consultation with Healthcare Professionals For individuals concerned about their testosterone levels, seeking guidance from experienced healthcare providers is advisable. Comprehensive blood tests and consultations can help determine appropriate treatments or lifestyle adjustments to address low testosterone.




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