Monday, February 26, 2024

Will Testosterone Therapy Help Me Sleep?

Understanding the Relationship Between Testosterone and Sleep in Men.


Testosterone, primarily linked to male reproductive health and secondary sexual traits like sperm production, fertility, deep voice, and muscle growth, surprisingly influences sleep patterns significantly. The intricate connection between testosterone and sleep entails a complex interplay, where disturbances in sleep can affect testosterone levels and vice versa.



Normally, hormone levels follow the body's natural rhythm, and peak while sleeping Research on the nocturnal testosterone rhythm in males have shown testosterone levels are at their highest around 8 in the morning and lowest around 8 p.m. at night, with sleep helping this normal cycle of testosterone production. However, not enough rest or sleeping disorders such as obstructive sleep apnea (OSA) may interfere with the natural rhythm, possibly influencing T levels. Scientists have discovered that by gaining one extra hour of sleep at night, a man could possibly raise their testosterone production. Researchers have tested sleep and testosterone production, and lack of sleep often causes an uptick in cortisol levels as well as a drop in testosterone.

Similar research has shown that insufficient sleep and sleep disorders could impact testosterone levels, confirming previous suspicions and findings by scientists. For example, a study on healthy young men revealed that sleeping less than five hours per night for a week resulted in a 10-15% reduction in testosterone levels.

Moreover, obstructive sleep apnea (OSA) has been associated with reduced testosterone levels, although it's uncertain whether OSA directly triggers low levels or vice versa. There's evidence indicating that addressing OSA could potentially elevate testosterone levels, underscoring the mutual influence between sleep and testosterone.

Sleep disruptions are linked to low testosterone levels in men. Symptoms of low testosterone may include:

    1. Decreased sex drive (libido)
    2. Erectile dysfunction or difficulty maintaining erections
    3. Fatigue or decreased energy levels
    4. Loss of muscle mass or strength
    5. Increased body fat, particularly around the abdomen
    6. Decreased bone density or osteoporosis
    7. Mood changes, such as irritability, depression, or anxiety
    8. Decreased cognitive function or difficulty concentrating
    9. Insomnia or sleep disturbances
    10. Decreased facial or body hair growth
    11. Hot flashes or excessive sweating
    12. Decreased motivation or drive
    13. Infertility or reduced sperm count
    14. Gynecomastia (enlarged breast tissue in males)
    15. Decreased physical stamina or endurance.

low T symptoms: When low testosterone (T) symptoms disrupt sleep, insomnia-like issues can arise, exacerbating the cycle of low T. Rest is crucial for hormonal health, requiring guidance from sleep-related experts:
  1. Sleep Medicine Specialists: Experts in diagnosing and treating sleep disorders.
  2. Pulmonologists: Specialize in respiratory issues, including sleep-related breathing disorders.
  3. Neurologists: Manage sleep disorders related to neurological conditions.
  4. Otolaryngologists (ENTs): Address upper airway issues contributing to sleep problems.
  5. Psychiatrists or Psychologists: Assist with sleep disorders linked to psychiatric conditions.
  6. Primary Care Physicians (PCPs): Evaluate and refer patients to specialists for further treatment.
  7. Dentists (Dental Sleep Medicine Specialists): Provide oral appliances for sleep apnea or snoring.
  8. Pediatricians: Address sleep issues in children and adolescents.
  9. Geriatricians: Focus on sleep disorders common in older adults.
  10. Certified Sleep Technologists: Conduct sleep studies and aid in diagnosis under specialist supervision.

testosterone therapy for women.

On the flip side, elevated testosterone levels might affect sleep quality, though the connection is complex. While high testosterone doesn't always manifest symptoms in males, studies suggest a potential correlation between poor sleep and elevated testosterone, especially with high-dose synthetic testosterone treatment. In females, conditions like polycystic ovary syndrome (PCOS), marked by high testosterone levels, can lead to sleep disturbances. Symptoms of high testosterone in women include excessive hair growth, male-patterned hair loss, deepening voice, acne, and irregular periods. Low testosterone levels in women can also impact health negatively, prompting some to consider testosterone therapy for women (BHRT). Proper understanding of signs, symptoms, and blood work interpretation is crucial in determining the appropriate course of action for each individual.



Testosterone replacement therapy Testosterone Replacement Therapy (TRT) is a common treatment for individuals with low testosterone levels. While TRT can enhance sleep quality for some, it carries risks, especially in high doses or certain medical conditions. Expert guidance from a qualified doctor is crucial due to potential complications, such as exacerbating obstructive sleep apnea or disrupting sleep patterns. Careful monitoring and personalized treatment plans from licensed healthcare providers specializing in this field can lead to transformative improvements in overall health and wellness. Men who want to learn more about how they can get a prescription for testosterone can talk to their doctor or look for guidance from a medical specialist like an endocrinologist, urologist or HRT/Low T specialist.

In summary, the relationship between testosterone and sleep is complex and reciprocal. Sleep disruptions can influence testosterone production, and abnormal testosterone levels can impact sleep quality. Recognizing this intricate interaction is crucial for addressing sleep-related concerns in individuals with testosterone imbalances. It underscores the importance of thorough evaluation and customized treatment approaches offered by specialists in hormone replacement, endocrinology, or sleep medicine.



 

Friday, February 23, 2024

Exploring HCG vs. Gonadorelin in TRT: Patient Preference vs Availability and Supply

Patient-Centered TRT: Unveiling the Debate Between HCG and Gonadorelin



Navigating HCG Supply: Challenges and Solutions for TRT Patients at NovaGenix health and wellness. 

In the realm of Testosterone Replacement Therapy (TRT), the choice between Human Chorionic Gonadotropin (HCG) and Gonadorelin has become a pivotal consideration for both patients and clinicians alike. While HCG has long been a staple in TRT protocols, recent regulatory changes have prompted a shift towards Gonadorelin in some clinics. However, questions linger regarding efficacy, cost, availability, and patient preference between these two medications. This article discusses into the intricacies of this debate, offering insights into the comparative aspects of HCG and Gonadorelin in TRT and shedding light on the factors influencing the decision-making process for both providers and patients. Well answer common questions like, “Which medication is better?” “Does Gonadorelin work?” “Can I still get hCG?”

1. Can I get HCG prescribed still?

Yes, HCG can still be prescribed for patients if it is their preference, despite many clinics generally prescribing Gonadorelin. hCG is still legal, available and quite effective. NovaGenix recognizes and respects the patient's choice in medication and strongly advises patients as to which medication is best suited for their therapeutic needs. We confidently recommend hCG over Gonadorelin for its superior benefits and overall patient satisfaction.

2. What is the cost difference between Gonadorelin and HCG?

Patients on TRT typically spend $30-50 per month for a therapeutic dose of Gonadorelin, while a therapeutic dose of HCG can cost $70-100 per month. It is important to note that the price and supply of HCG are not under the control of the prescribing clinic, which can lead to temporary unavailability or price increases. Fortunately for our patients we have pharmacy partners that are able to assist us and have been able to meet patient demands.



3. What is the risk of running out of medication and experiencing changes in hormone levels with hCG or Gonadorelin?

Currently here is no risk of running out of hCG. Our focus is making sure that patients don’t run out of medications while on testosterone replacement placement therapy (TRT). In the future, the FDA can always make regulatory and legal changes to medication classification and with pharmacies ability to manufacture and dispense medications, but for now we are confident in the supply of therapeutic options available for our patients. There seems to be no shortage of Gonadorelin either, however more patients reach out to us looking to switch back over to hCG after trying gonadorelin, as they feel the effects from hCG are way more noticeable.

4. Is it easy to find a pharmacy that can fill Gonadorelin prescriptions?

Yes, it is extremely easy to find a pharmacy that can fill Gonadorelin prescriptions for patients. They do not have to spend any time or energy in getting their prescriptions filled, as it is conveniently delivered to their doorstep with their other TRT medications.

5. Is it easy to find a pharmacy that can fill hCG prescriptions?

No. unfortunately after the FDA made regulatory changes which now limits the number of pharmacies that can make hCG. There are only 81 503b-compounding pharmacies that are approved by the FDA to produce hCG and FSH, and only 5 of them actually manufacture the medication. This has increased the demand and caused a massive decrease in supply. Fortunately NovaGenix works with pharmacies able to dispense hCG to patients.



6. How does Gonadorelin compare to HCG in terms of potential adverse effects?

Gonadorelin has slightly less potential for adverse effects compared to HCG. HCG can cause the testicles to produce more estrogen directly because it helps produce more testosterone, whereas Gonadorelin does not have this effect. Many patients who have taken both medications have reported better positive effects with hCG in regard to symptom resolution making it our top choice.

7. What are the physical symptoms associated with testicular shrinkage?

Testicular shrinkage can result in smaller testicles, a less full scrotum, and reduced ejaculate. These symptoms can make men feel less masculine and potent. Some men report an aching sensation in their testicles. Our experience is that hCG works better for reversing these symptoms in men who are on TRT.



8. Why do some doctors generally prescribe Gonadorelin instead of HCG?

Some clinics and doctors will prescribe Gonadorelin instead of HCG primarily because they cannot obtain hCG due to the limited supply and high demand. The ability of hCG to maintain fertility and reverse testicular atrophy is far superior as compared to other choices like gonadorelin. Fortunately for our patients, NovaGenix is a clinic that can still prescribe hCG.

9. Which medication do patients prefer?

Universally, we have found that our patients that have tried gonadorelin have not felt the desired effects. Clinical studies that have shown benefits of gonadorelin had been seen when patients were taking doses multiple times a day, and used a pump inserted into their skin to deliver the medication. In the study, patients were administered 10 μg every 90 min subcutaneously using a Hypophyseal Hormonal Infusion Pump. This is not useful for patients on TRT and the efficacy of hCG was may for evident with only a twice weekly subcutaneous injection. hCG for men on TRT is by far the winner. 



Monday, February 19, 2024

Navigating Hormonal Balance: The NovaGenix Approach to Testosterone Therapy

 

Unlocking Vitality: Testosterone Therapy Programs Revolutionizing Men’s Health



In the pursuit of optimal health and well-being, men often seek solutions that go beyond conventional approaches. For many males grappling with the effects of low testosterone levels, NovaGenix emerges as a top rated Low T clinic, offering a comprehensive testosterone therapy program that transcends traditional methodologies. As we look into the realm of testosterone replacement therapy (TRT), let's explore hormone replacement and how it recently has become a game changer for men offering accessibility and effectiveness when dealing with the effects of aging and Low T.

Understanding the Need for Testosterone Therapy

Low testosterone levels, often referred to as hypogonadism, can manifest in various symptoms ranging from fatigue, reduced libido, loss of muscle mass, to mood swings. While these symptoms can significantly impact one's quality of life, many individuals remain unaware of their underlying hormonal imbalance. When men start to hit their late 30’s or 40’s they start to really notice some of the telltale signs and symptoms. Taking naps after work, reduced quality and frequency of erections with a decreased libido/ low sex drive. Loss of strength and muscle mass, fatigue and brain fog are all common. This is where NovaGenix steps in, providing specialized care to diagnose and address these issues effectively. You can get tested, diagnosed, and treated with all-inclusive treatment plans with US based pharmacies delivering all medications straight to your home or office. For men looking to find a doctor who prescribes testosterone, NovaGenix is the answer.



Accessibility: TRT Therapy Near Me

One of the primary concerns individuals face when considering testosterone therapy is accessibility to quality care. With NovaGenix, this concern is alleviated as they offer convenient locations and telemedicine appointments, ensuring that individuals can access their services without extensive travel. You can get blood work performed at a LabCorp location located close to your home. Dr. Mackey will review these labs and have an in-depth consultation going over signs and symptoms as well as your past medical history to determine testosterone rx eligibility. Whether you're in bustling urban centers or quieter suburban areas, NovaGenix ensures that their physician and medical team are within reach, making the journey to hormonal balance seamless. Just send an email, call or text and you’ll be taken care of by a staff with over 20 years of experience in men’s health and hrt.

Expertise: Doctors That Can Prescribe Testosterone

Central to NovaGenix's success is its team of experienced medical professionals specializing in hormone therapy. These doctors and medical staff possess the expertise necessary to accurately diagnose hormonal imbalances and tailor treatment plans to meet each patient's unique needs. Moreover, NovaGenix prioritizes patient education, ensuring that individuals are empowered with knowledge about their condition and treatment options. Whenever a question comes up, the team at NovaGenix is always available for guidance and support. We have patients transfer over from other medical clinics who complain about the difficulty in getting help and support, but at NovaGenix, you’ll never have that issue as we’re accessible to patients whenever they need us. For men looking for what type of doctor prescribes testosterone, look no more as we have you covered with a licensed and experienced physician.



Tailored Approach: Most Effective Testosterone Replacement Therapy

What sets NovaGenix apart is its commitment to personalized care. Recognizing that every individual's physiology is unique, NovaGenix adopts a tailored approach to TRT. Through comprehensive evaluations and advanced diagnostic techniques, they develop customized treatment regimens optimized for efficacy and safety. Whether it's testosterone injections, creams, or capsules, NovaGenix offers the most effective modalities tailored to individual preferences and medical considerations. We can help offer guidance and support about medications like gonadorelin, enclomiphene, clomid and hCG and address concerns over possible side effects as well as the timeline as to when one can expect to see the benefits from starting TRT.



Affordability: TRT Without Insurance

Financial concerns should never hinder individuals from accessing vital healthcare services. NovaGenix understands this and offers TRT solutions that accommodate various financial circumstances. For those without insurance coverage, NovaGenix provides transparent pricing structures and flexible payment options, ensuring that cost is not a barrier to receiving the care needed to reclaim vitality and well-being. With healthcare you get what you pay for, so NovaGenix offers top quality medical care and medication from licensed and accredited US based pharmacies. Patients need not worry about the dangers from dangerous online pharmacies that offer untested medications, but instead get a legal TRT prescription from a qualified and experienced doctor. Lot’s of patients ask “is TRT is covered by insurance?” which we tell them to check with their insurance provider as each plan is different and eligibility requirements vary considerably. All inclusive TRT plans from a testosterone clinic offer convenience, flexibility, affordability and expertise from a staff dedicated to men’s hormonal health.

The Road to Vitality Begins with NovaGenix

NovaGenix's testosterone therapy program transcends the conventional approach to hormonal imbalance treatment. By combining accessibility, expertise, personalized care, and affordability, NovaGenix empowers individuals to reclaim their vitality and rediscover a life filled with energy, vigor, and vitality. Whether you're seeking TRT therapy near you or searching for doctors that can prescribe testosterone with unparalleled expertise, NovaGenix stands as a beacon of excellence in the realm of hormone therapy. Take the first step towards a healthier, more vibrant life with NovaGenix today.



 

Friday, February 16, 2024

Does Testosterone Therapy Cause Infertility?

Will Being on TRT Make a Man Sterile?

Understanding the effects of testosterone on male fertility and reproductive functioning.

We are often asked by men interested in starting TRT the question “Does testosterone therapy cause infertility?” Testosterone replacement therapy in men is a popular therapeutic treatment option for men with low T looking to improve their overall health, wellness, and vitality, but what about its effect on sperm production and fertility in male patients? TRT is often prescribed to address various health concerns in men, with signs and symptoms such as fatigue, low libido, mood swings, decreasing muscle mass and weight gain. Yet there are significant questions and concerns about its impact on male fertility.  While testosterone therapy can provide relief from these and other symptoms associated with low T, (also known as hypogonadism), its effects on male fertility are complex and multifaceted and worth discussing.

To understand the relationship between testosterone therapy and male fertility, it's essential to grasp how testosterone is produced and how it affects the male reproductive system. Testosterone, the primary male sex hormone, plays a crucial role in sperm production, libido, and overall sexual function. Therefore, alterations in testosterone levels can have profound implications for fertility. Testosterone production in men primarily occurs in the testes, specifically within specialized cells called Leydig cells. Every male will have a different testosterone level so it’s difficult to say exactly what a normal testosterone level is.

These cells, located in the interstitial tissue surrounding the seminiferous tubules, respond to hormonal signals from the hypothalamus and pituitary gland. This intricate process, known as the hypothalamic-pituitary-gonadal axis, regulates testosterone synthesis. The pituitary gland secretes two key hormones to stimulate testosterone and sperm production in men: luteinizing hormone (LH) and follicle-stimulating hormone (FSH). LH signals the Leydig cells in the testes to produce testosterone, while FSH stimulates the production of sperm in the seminiferous tubules. This coordinated action regulates male reproductive function.

One of the primary concerns with testosterone therapy is its potential to suppress sperm production, leading to a decrease in sperm count and quality. Testosterone replacement therapy (TRT) works by supplementing the body with exogenous testosterone, which can signal the brain to reduce its natural production of the hormone. This decline in endogenous testosterone production can, in turn, inhibit the production of sperm in the testes, ultimately affecting male fertility. So TRT may contribute to a decline in sperm count and fertility, but it should be noted that TRT is not an effective form of contraception in men, as it’s a common misconception. This is not the case at all, and precautions should be taken if one is trying to prevent pregnancy. TRT doesn’t prevent men from being able to impregnate women and many men can even improve fertility while on proper treatment while under a physician’s care. This is not the case at all and all precautions should be taken if one is trying to prevent pregnancy.

There have been several studies worth noting that have explored the impact of testosterone therapy on male fertility, yielding mixed findings. Some research suggests that testosterone therapy can indeed suppress sperm production, leading to a decline in sperm count and motility. However, the extent of this effect can vary depending on factors such as the dosage of testosterone administered, the duration of treatment, and individual patient characteristics.

It's worth noting that testosterone therapy is not always associated with infertility. In some cases, men undergoing TRT may experience improvements in fertility-related parameters, such as sperm count and motility. This paradoxical effect may be attributed to the normalization of testosterone levels, which can optimize sperm production and enhance overall reproductive function.

Furthermore, the impact of testosterone therapy on male fertility may be influenced by the underlying cause of hypogonadism. In men with primary hypogonadism (testicular failure), testosterone therapy may have a more pronounced effect on sperm production compared to those with secondary hypogonadism (hypothalamic-pituitary dysfunction). In secondary hypogonadism, the impairment lies within the hypothalamus or pituitary gland, and testosterone therapy may not disrupt sperm production to the same extent.

Men on testosterone replacement therapy (TRT) who wish to improve fertility can explore several methods:

HCG Therapy: Human chorionic gonadotropin (HCG) can mimic the action of LH in the body, stimulating the Leydig cells to produce testosterone. This can help maintain healthy testosterone levels while also supporting sperm production.

 

Taking LH (luteinizing hormone) and FSH (follicle-stimulating hormone): These medications can potentially increase sperm count. LH and FSH are crucial hormones involved in the production of sperm in the testes. By stimulating the Leydig cells (LH) and Sertoli cells (FSH) in the testes, these hormones play a key role in spermatogenesis. Therefore, administering LH and FSH through medications or treatments can help boost sperm production, which may ultimately increase sperm count.

 

Enclomiphene and Clomiphene Citrate: This medication can stimulate the release of LH and FSH from the pituitary gland, thereby enhancing testosterone and sperm production. It's often used in combination with TRT to preserve fertility. Enclomiphene is a nonsteroidal selective estrogen receptor modulator (SERM) that is used to treat hypogonadism in men. It works by blocking estrogen receptors in the brain, which leads to increased production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This, in turn, stimulates the testes to produce more testosterone. Enclomiphene is typically prescribed to men with low testosterone levels to help restore hormonal balance and improve symptoms associated with low testosterone.

Clomid, also known by its generic name clomiphene citrate, is a medication commonly used to treat infertility in women. However, it can also be prescribed off-label for men with low testosterone levels or hypogonadism. Clomid works by blocking estrogen receptors in the brain, which triggers the release of hormones like luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This stimulates the testes to produce more testosterone. In men, Clomid is sometimes used as an alternative to testosterone replacement therapy (TRT) to boost testosterone levels and improve symptoms associated with low testosterone. Whether hCG or Clomid is better depends on each patients response and physician preference.

 

Adjusting TRT Dosage: Sometimes, by simply adjusting the dosage of testosterone a patient takes, it can help balance hormone levels and improve fertility. Lowering the dose or switching to a different delivery method may be beneficial and something that needs to be carefully discussed with your prescribing healthcare provider.

 

Lifestyle Changes: Adopting a healthy lifestyle can also help to support fertility. This includes maintaining a healthy balanced diet, getting regular exercise, reducing stress, getting enough sleep each night, and avoiding excessive alcohol and tobacco use. This can often be hard to do, but the logic is sound and the effects have been well documented.

 

Consulting a Specialist: Men considering TRT who are concerned about fertility should consult with an expert in hormone replacement therapy, fertility specialist or endocrinologist. They can provide personalized guidance and may recommend additional treatments or interventions tailored to individual needs and goals. Not everyone has the same past medical history, goals or needs and this must be taken into consideration when creating a patient’s protocol.

Despite the potential risks associated with testosterone therapy, it remains a valuable treatment option for men with hypogonadism, especially when accompanied by debilitating symptoms. However, clinicians must carefully weigh the benefits of TRT against its potential impact on male fertility, particularly in men of reproductive age who want to start a family and have children.

To mitigate the adverse effects of testosterone therapy on fertility, several strategies can be employed by an experienced and qualified doctor. For instance, the provider may recommend combining testosterone therapy with adjunctive treatments aimed at preserving or enhancing fertility, such as human chorionic gonadotropin (hCG) or selective estrogen receptor modulators (SERMs). These adjunctive therapies can help maintain testicular function and support sperm production while undergoing testosterone therapy.

Additionally, regular monitoring of reproductive parameters, including sperm count, motility, and morphology, is essential for men undergoing testosterone therapy who are trying to get their partners pregnant and have kids. Close surveillance allows clinicians to assess the impact of treatment on fertility and make necessary adjustments to minimize adverse effects. There is a “sweet spot” where the body requires testosterone for sperm production and reproductive health. Too much or too little can impact fertility, so a knowledgeable physician is important for helping to reach these goals.

In conclusion, testosterone therapy can exert complex effects on male fertility, with implications that vary depending on unique individual factors and treatment characteristics. While TRT may suppress sperm production in some men, it can also improve fertility-related parameters in others.  There is no one size fits all solution when it comes to HRT. Clinicians must carefully evaluate both the benefits and potential side effects of testosterone therapy, considering its impact on male fertility and overall reproductive health for each patient and decide the best path forward. By adopting a personalized approach and implementing appropriate monitoring measures, clinicians can optimize the therapeutic outcomes of testosterone therapy while safeguarding male fertility.

Website: www.NovaGenix.org Telephone: (561) 277-8260 email info@novagenix.org