Does Testosterone Therapy Cause Prostate Cancer?

The Relationship Between Testosterone Replacement Therapy (TRT) and Prostate Cancer: What You Should Understand

Is There a Link Between TRT and Prostate Cancer?

Navigating the connection between testosterone replacement therapy (TRT) and  prostate cancer involves understanding a complex interplay. While increased testosterone levels don’t directly cause prostate cancer, they can influence the growth of existing prostate cancer cells.

Consulting a healthcare professional is essential before initiating TRT, ensuring personalized advice based on individual health and medical history. An essential preliminary test is the PSA test  (PSA blood test). Prostate-specific antigen (PSA), a protein produced by both normal and cancerous prostate cells, is analyzed in the bloodstream. Elevated PSA levels can signify prostate cancer and warrant further investigation.

Initially approved by the FDA in 1986 to monitor prostate cancer progression, the PSA test later gained approval in 1994, alongside a digital rectal exam (DRE), for detecting prostate cancer in men aged 50 and older.

The American Association of Urology underscores that testosterone therapy isn’t linked to prostate cancer development. Randomized controlled trials suggest no significant rise in prostate cancer diagnosis rates in older, testosterone-deficient men treated with testosterone compared to a placebo.

According to the American Association of Urology

“Clinicians should inform patients of the absence of evidence linking testosterone therapy to the development of prostate cancer.”

“There is accumulating evidence against a link between testosterone therapy and prostate cancer development. Randomized controlled trials have shown that there is not a significant increase in the rate of a prostate cancer diagnosis in older, testosterone deficient men who were treated with testosterone compared to placebo”

Understanding the Prostate:

The prostate, a small gland in the male reproductive system situated under the bladder and in front of the rectum, surrounds the urethra. Its primary role involves producing fluids contributing to semen along with sperm from the testes and other gland secretions.

Identifying Prostate Cancer Symptoms:

Early-stage prostate cancer may lack noticeable symptoms. As it progresses, signs may include urinary changes, blood in urine or semen, erectile dysfunction, discomfort in the pelvic region or lower back, and unexplained weight loss or fatigue. These symptoms may indicate other medical conditions, emphasizing the importance of medical consultation and regular screenings, particularly for those at higher risk.

Prostate Cancer Treatments:

Treatment approaches vary based on cancer stage and overall health. Treatments encompass surgery, radiation therapy, hormone therapy, chemotherapy, immunotherapy, and active surveillance—monitoring without immediate medical intervention. Decisions on treatment involve collaborative discussions between patients and healthcare teams comprising various specialists.

Hormone Therapy for Prostate Cancer:

Hormone therapy often involves reducing androgen levels like testosterone that could accelerate prostate cancer cell growth. Medications block testosterone production or its effects, slowing cancer growth. This approach is common for advanced prostate cancer and may be used alone or combined with other treatments, tailored to individual patient needs.

Detecting Prostate Cancer:

Methods for detection include digital rectal exams, PSA tests, biopsies, and imaging studies. Regular screenings and discussions with healthcare providers are pivotal, especially for those with risk factors or symptoms, enabling early detection and proactive management.

Visit us online at www.NovaGenix.org to learn more or call/text us at 561-277-8260 to schedule an appointment to speak with a licensed and experienced doctor